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Image Search Results
Journal: Oncology Research
Article Title: Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma
doi: 10.32604/or.2024.046231
Figure Lengend Snippet: FAK promotes the EMT of HCC. E-cadherin expression was lower, and vimentin expression was higher in liver cancer tissues with high FAK expression compared with paracancer tissues with low FAK expression (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001) (A) Action diagram. FAK phosphorylation inhibitors can inhibit FAK phosphorylation. FAK PROTAC inhibited the kinase-dependent and non-kinase-dependent functions of FAK by degrading FAK. (B) Experimental flow chart (C).
Article Snippet: Defactinic, an
Techniques: Expressing